High-grade serous ovarian cancer (HGSOC) is a subtype of epithelial cancer originating from thefallopian tubes and it is a the most abundant and lethal subtype of epithelial ovarian cancer.The standard treatment for HGSOC consists of surgery and platinum-taxane chemotherapy,and even though 80% of patients have an excellent initial response, the majority relapse within18 months leading to less than 45% 5-year survival rate. Thus, it is important to develop toolsto predict the patient’s response and identify which patients who benefit from the treatment.This study focuses on using prospectively collected samples from 37 HGSOC patients, specificallyhematoxylin and eosin stained(H&E) histopathological images corresponding to primarytreatment phase, in order to predict the response to chemotherapy in HGSOC.The study is mainly composed by two phases.