The kidneys perform numerous essential regulatory functions, including the ability to purify the blood, maintain electrolyte balance and a physiological pH, and when these are no longer properly carried out, acute kidney injury (AKI) appears, a clinical condition that represents a risk factor for morbidity and mortality, which causes the death of about 2 million people per year and whose long-term effects lead to the development of chronic kidney disease (CKD) and end-stage renal disease (ESRD). There are several renal replacement therapies (RRT), the most widely used is Continuous Renal Replacement Therapy (CRRT) which, through an extracorporeal circuit which includes a semipermeable filter, allows removal rates of solutes and toxins in a continuous, gradual and slower way compared to intermittent haemodialysis, thus closely approaching the physiological condition.