This thesis presents an analysis of the main excavation data regarding the Grottaminarda tunnel, excavated using an EPB-TBM, almost in closed mode and under hyperbaric conditions. Chapter 2 will provide a brief introduction to the geological-geomechanical context of the area, in order to describe the main issues to be addressed throughout the section under investigation. Chapter 3 and Chapter 4 will present the predictive models used by the designers to determine the necessary machine parameters for excavation, and the P.A.T. (TBM Advancement Protocol). The latter is the "guideline" for the various work teams on site, essential for achieving proper progress in terms of pressures, thrust, torque, excavation volumes, and other machine-soil parameters.