The growing complexity of space systems and missions is causing a rapid increase of onboard data size, to the point where efficient data compression algorithms become essential. The resource constrained environment requires careful consideration of how to optimize this procedure. On the other hand, NOEL–V is emerging as a promising space-grade processor, offering both high performance and reliability for critical space applications. Being built on the RISC–V ecosystem, NOEL–V inherits its ability to enhance performance through the integration of hardware accelerators with the processor. Tightly-coupled and loosely-coupled accelerators (TCAs and LCAs respectively) offer different benefits: the former are more compact but require more effort to integrate them, while the latter should be carefully designed to minimize their area.