Optical Coherence Tomography Angiography (OCTA) is an emerging non-invasive, high-resolution imaging technique used in dermatology for visualizing skin vasculature. Images are acquired through a probe brought in contact with the skin surface; however, this modality can introduce mechanical stress to the skin and temporarily change the underlying vascular structure, compromising the accuracy of OCTA images. Therefore, the pressure applied by the OCTA probe is a critical factor that can affect the repeatability of acquisitions and reliability of the resulting data. This thesis aims to analyze how OCTA probe pressure may affect the accuracy and quality of angiographic images, evaluating the impact via specific metrics and validating the results through statistical analysis.