This thesis analyzes the relationship between the location of assistance centers for homeless people and the processes of marginalization and segregation in urban contexts. A facility, service or care center for people in extreme vulnerability and exclusion -such as homeless people- with an unstrategic location can aggravate the conditions they are intended to mitigate. The location of these centers can reinforce social exclusion, territorial stigmatization and the vulnerability of both the user and the context. With the application of a critical, qualitative and spatial analysis, this research detects how the implementation of these centers with a scarce critical and consequentanalysis of the territory, can perpetuate exclusion both at the individual and community level, creating a vicious circle of marginalization.