Alice Giordano
Data-driven nonlinear control of glucose-insulin dynamics in patients affected by Type I Diabetes.
Rel. Diego Regruto Tomalino. Politecnico di Torino, Master of science program in Mechatronic Engineering, 2024
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Abstract
Diabetes is one of the top ten causes of death in adults and, in the last decades, became a global health problem. People with T1DM suffer from a metabolic disorder characterized by pancreas inability to produce a sufficient amount of insulin, the peptide hormone that plays a vital role in regulating the way cells absorb glucose and use it as an energy source. As a result, these individuals need to constantly control their blood glucose levels through insulin administration. In recent years, significant technological progress in continuous glucose monitoring and insulin delivery systems has enabled researchers to develop automated methods for managing diabetes, often referred to as the Artificial Pancreas.
The development of control algorithms for this purpose is a highly active field of research
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