This master degree thesis explores how parametric design, simulation, and optimization methodologies intertwine, showcasing their effectiveness in architectural design across various geographical contexts. Specifically, firstly, We found a way to design an imagined box office with parametric skill, then build it within a 3D software environment. Secondly, we managed to evaluate it in 3 perspectives, which are economical assessment, energy need intensity and comfort performances. Thirdly, we applied a genetic algorithm on it to get the optimized results, and repeat the experiment under different climate conditions. Lastly, we collect the result, visualize it and analyse it. We published the result and the workflow on Internet, in order to get feedback.