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Investigating microbial interactions in the chicken gut microbiome: a comparative co-occurrence network analysis of Antibiotic Growth Promoters (AGPs) and Phytogenic Feed Additives (PFAs) over time.
Rel. Stefano Berrone. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Matematica, 2024
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Abstract
The use of antibiotics as growth promoters (AGPs) in the poultry industry raises global concerns about antimicrobial resistance (AMR). As an alternative, phytogenic feed additives (PFAs) are gaining interest for their potential to enhance intestinal health and animal performance without worsening AMR. The effects of both the AGP and PFA treatment remain unclear. For this reason, a thorough analysis is needed to understand how these feed additives impact the poultry microbial community. In this study, we hypothesized that the poultry microbial microbiome would respond to the feed additives, leading to a healthier community structure with more efficient dynamics. To confirm this, we aim to use co-occurrence networks and network anal??ysis to investigate the effects of antibiotic growth promoters (AGPs) and phytogenic feed additives (PFAs) on the cecum microbial communities in the chicken gut.
This approach allows us to visualize and quantifies complex interactions among various mi??crobial taxa, providing a more detailed understanding of the dynamics within the micro??bial community
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