Vittorio Barbano
Poly-(l)-lactic acid and Hydroxyapatite nanopowder composite scaffold for bone regeneration in the biomedical field.
Rel. Stefania Specchia, Elia Marin. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Chimica E Dei Processi Sostenibili, 2024
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Abstract
Due to the aging population, the need for new materials for bone regenerations that can substitute natural bone is increasing. With the requirement of biodegradability and biocompatibility, many possibilities have been developed in recent years. In this thesis, a composite made with poly-(l)-lactic acid (PLLA) and hydroxyapatite has been developed and characterized. The amount of hydroxyapatite was chosen as a weight percentage of PLLA, in particular 1, 5 and 10 percent. The composite was made by solubilizing PLLA in chloroform and dispersing hydroxyapatite in the solution via bath sonication. The samples were ground and then dried in vacuum oven. Melt electro-writing 3D printing was then used to print square scaffolds with 1x1 cm size, 0.6 mm of thickness and a pore size of 200 μm.
Laser microscope and SEM analyses were used to show the structure of the scaffold after printing and its change with the amount of hydroxyapatite
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