The engine acoustic character has always represented the product DNA, owing to its strong correlation with in-cylinder pressure gradient, components design and perceived quality. Best practice for engine acoustic characterization requires the employment of a hemi-anechoic chamber, a significant number of sensors and special acoustic insulation for engine ancillaries and transmission. This process is highly demanding in terms of cost and time due to multiple engine working points to be tested and consequent data post-processing. Since Neural Networks potentially predicting capabilities are apparently un-exploited in this research field, the following paper provides a tool able to acoustically estimate engine performance, processing system inputs (e.g.