Structural monitoring is a process used to assess stability and performance of structures over time and it consists of a measurement phase followed by a data processing phase. It is mainly applied on infrastructures of significant socioeconomic value, such as transportation networks. In Italy the recent investigation campaign following the legislative actions due to the Morandi Bridge collapse in Genova, has revealed a critical situation nationwide extended, whereby a significant portion of existing post-war infrastructure present such deficiencies that designers and policymakers often must face the decision between their restoration or reconstruction. This situation has made it clear how the almost total absence of monitoring data on the investigated structures, significantly limits the ability to define their effective health status.