Over the recent years, powertrain development has been characterized by a significant rise to face with the more restrictive emissions limitations. Despite the harsh criticism that the public opinion is levelling at Diesel engine, it has been involved into this rush to technological innovation. The vehicle industry is a competitive business and Original Equipment Manufacturers (OEMs) are forced to invest in innovative strategies with high complexity level and to study a wide range of working conditions, paying attention to keep the costs to a minimum. To achieve these targets, as well as accuracy, safety and repeatability of the tests, virtualization is the surely one the best ways to be followed, and modelling is an increasingly important field for research and development [2,3].