My master thesis project stems from the beginning of a collaboration between the Polytech- nic University of Turin and the Molecular Biotechnology Center (MBC) of the University of Turin. The aim of my project is the development of a platform for impedance measurements on cell cultures, finalised to drug screening studies. Changes of an electrical parameter as impedance reflect changes in the cells’ status: in particular, an increase in impedance is index of viability and proliferation, while an impedance decrease represents cell death. To this aim, a commercial device, the BioChip 4096E (3Brain GmbH, Switzerland) was employed and seeded with cells, since its design integrates the presence of a culture cham- ber and a certain number of electrodes, giving the possibility to conduct impedance meas- urements.