Voice is essential for communication, relationship building, and emotional expression: its production involves the vocal cords, respiratory system, and upper vocal tract, and improper control can lead to dysphonia. Multiple Sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system that can result in physical disabilities, including voice disorders, in fact 62% of MS patients experience hypophonia. The Don Gnocchi Foundation supports patient’s rehabilitation, mainly with the Lee Silverman Voice Treatment (LSVT)-Loud, an effective therapy based on motor learning and neural plasticity principles. Traditionally offered in person, LSVT-Loud has recently transitioned online due to COVID-19, allowing patients to receive therapy at home without needing transportation or accompaniment, which improves accessibility and convenience.