According to the latest agenda issued by the International Council of Museums (ICOM) – the world’s leading organization for museums – cultural venues shall be intended as places where inclusion must hold a hegemonic place of attention throughout the curation, exhibition, and delivery phases. In addition to architectural barriers – formalized since the late 1960s in the Italian law and practices - such venues must indeed consider neurodivergence as a new variable of inclusion and accessibility – aided by the digitization of the cultural heritage, which is yet another priority of this new agenda. Indeed, between 15 and 20% of the world population hold a form of neurodiversity – thus altering the perception and reception of cultural experiences, which are often designed from and to the perspective of neurotypical individuals.