Synthesis and characterization of Carbon Dots as platforms for DADS loading

CDs are carbonaceous materials with nanometrical dimensions commonly defined as zero-dimension materials. These materials are biocompatible, easy to prepare, photostable and their production cost is relatively low. However, photoluminescence is undeniably the most compelling feature of the material, rendering its application suitable for the bioimaging and the theragnostic field. The variables in the creation of a material with diagnostic and therapeutic purposes are countless. The perfect material has a good balance in its polarity to reach the cell in its environment, a high yield in its production, a high yield in the loading process, and it has to penetrate the cellular barrier easily among other things. To satisfy all these criteria, a countless compounds library becomes crucial. This work and its characterization intend to produce different products in order to direct future syntheses. Moreover, this work aims to combine the diagnostic properties of Carbon dots with the therapeutic effects of Diallyl Disulphide. To reach its scope, this thesis starts with the synthesis and characterization of a specific class of carbon dot. A further characterization provides the information to properly choose the carbon dot suitable for the second process: the Dyallil Disulfide loading. Three different types of symmetrical unsaturated disulfide compounds are loaded in order to calculate the yield of the absorption process. Furthermore, the full characterization provides the information to understand the material entirely, allowing the simulation of the product with HyperChem software.