Carlo Loddo
Quantitative assessment of posture instability in Parkinson's disease patients using smartphone sensors.
Rel. Gabriella Olmo. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Biomedica, 2019
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Abstract
Parkinson's disease (PD) is a neurodegenerative disorder that mainly affects movement and compromises the quality of life. Motor fluctuations (alternation of ON and OFF states) usually appear after several years of levodopa use. In particular, during the OFF state, one of the main problems are falls and their possible consequences. The aim of the study was to find a quantitative method for the patient's motor assessment. In fact, the most used clinical scale, the MDS-UPDRS, does not exhibit a great objectivity and reproducibility. Moreover, the neurologist sees the patients only once or twice per year; this means that the doctor cannot observe short-term variations of the pharmacological or surgical treatments typical in PD patients.
A routine patient monitoring could enable the neurologist to track the evolution of the disease and adapt the drug posology
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