Continuous vital signs monitoring is of utmost importance for many people. Consequently, devices able to perform such monitoring, also called Personal Health System (PHS), have been gaining a lot of research and market interest in the last few years. This thesis work deals with the design of a comprehensive PHS able to perform EKG, measure heart rate (HR) and blood oxygen saturation (SpO2) as well as monitoring skin temperature and humidity and tracking activity. Vital EKG has a wrist band form factor. This choice simplifies the management of the device with respect to chest straps; EKG trace and SpO2 and HR readings are offered on demand and require the user to place two fingers on the device.