Objective: The purpose of this work is to create a portable and low-cost diagnostic instrument in ophtalmology, which replaces, at least in a first evaluation of the patient, the commercial instrument (Retimax CSO). Particularly aimed at the investigation of a signal called pattern reversal visual evoked potential (pr-VEP).Materials and Methods: Epson Moverio BT-200 Smart Glasses are used to generate the pattern reversal stimulus. Electroencephalographic signals, taken through 3 electrodes positioned following the 10/20 international system, is acquired by a commercial acquisition card (OpenBCI Cyton board) and is sent via bluetooth to a PC. Here, through a Matlab algorithm, the data are processed and filtered appropriately in real time, dividing them in epochs of length equal to the time window of stimulus of the reversal pattern and making the average between the epochs obtained.Statistical analysis and Results: After having set up the system introduced a year ago, a recalibration was done on 10 healthy subjects, then a preliminary validation on 11 pathologic subjects, for a total of 42 eyes analyzed.