Simone Gangemi
Modelling the deformability of pulmonary arteries in fluid-structure interaction simulations of percutaneous pulmonary valves.
Rel. Claudio Chiastra, Mariachiara Arminio. Politecnico di Torino, Master of science program in Biomedical Engineering, 2026
Abstract
The pulmonary valve (PV) is a semilunar heart valve that ensures the unidirectionality of blood flow from the right ventricle into the pulmonary artery (PA). Downstream of the PV, blood flows into the main pulmonary artery, which subsequently bifurcates into the right and left pulmonary arteries. Congenital heart diseases can compromise PV functionality, necessitating the implantation of a prosthetic device. In recent years, percutaneous pulmonary valves (PPVs), composed of a biological valve sutured on a metallic stent, have emerged as promising valve substitutes. The clinical outcome of PPV implantation is closely related to valve biomechanics and PA flow patterns. In this context, fluid-structure interaction (FSI) simulations enable the evaluation of the biomechanical interaction between blood flow, valve leaflets, and vascular walls.
Previous studies have computationally investigated the biomechanics of PV substitutes by means of FSI simulations
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