Lorenzo Luigi Stagno
Investigation of Motor Unit Discharge Patterns and Myotendinous Junction Dynamics during Isometric Contractions.
Rel. Taian Martins. Politecnico di Torino, Master of science program in Biomedical Engineering, 2026
Abstract
Precise control of skeletal muscle force relies on a complex interplay between neural drive and the mechanical properties of the muscle-tendon unit. Within this framework, the phenomenon of motor unit (MU) discharge rate hysteresis, quantified as ∆F , is commonly attributed to the activation of persistent inward currents (PICs) in spinal motoneurons. However, this interpretation typically assumes that synaptic input scales linearly with muscle force and often neglects the mechanical behavior of the muscle-tendon unit. Due to tendon compliance, muscle fascicles may undergo significant length changes even during globally isometric contractions, potentially influencing discharge rates through afferent feedback or intrinsic force-length properties.
This study investigated the contri- bution of muscle mechanics to MU firing patterns in the Tibialis Anterior (TA) muscle
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