Peripheral nerve injuries (PNIs) represent a challenging clinical problem to manage. Among the gold standard methods used to treat PNIs, there are autologous nerve grafting, nerve allografts, and nerve transfer. In addition to these techniques, nerve regeneration can be achieved through electrical stimulation (ES), which promotes neurite outgrowth, axonal myelination, and neuronal differentiation. However, the main limitation of these approaches lies in their invasiveness, particularly for ES, which requires electrode implantation with a consequent risk of inflammation of the surrounding tissues, making this method less suitable for long-term clinical applications. To overcome this limitation, recent studies in the field of nanotechnology have enabled the investigation of the behavior of magnetoelectric nanoparticles (MENPs) when placed in contact with excitable tissues.