Titanium and its alloys are widely used for biomedical implants and their long term performance is often set by the first events at the interface, most notably protein adsorption, which is strongly shaped by surface chemistry, wettability, and topography across multiple length scales. This thesis investigates surface structuring routes that are reproducible and suitable for clinically relevant titanium alloys, with the aim of tuning these early interfacial cues while keeping roughness at levels that do not promote bacterial proliferation. Electron beam (EB) surface structuring and ultrafast laser processing are used to generate groove-like patterns on Titanium Grade 2 (TiGr2), Ti-17, Ti-12Mo, and Ti-18Mo.