Alessandra Morri
Development of smart carriers for treating PTSD.
Rel. Chiara Tonda Turo, Piergiorgio Gentile. Politecnico di Torino, Master of science program in Biomedical Engineering, 2026
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Abstract
Post-traumatic stress disorder (PTSD) is a debilitating mental illness triggered by a significant frightful event such as war, natural disaster or violence. In the past, it was associated mainly with veterans, but nowadays, the incidence shows a rising trend, with a percentage of 3.9% of people worldwide who have declared to suffer from PTSD, especially correlated to the COVID-19 pandemic and the increasing war anxiety. The major associated symptoms are hyperarousal, sleep disorders, social anxiety and isolation, conditions that negatively affect the quality of life. The current therapies, cognitive behaviour and pharmacological therapies, focus on reducing symptoms rather than curing the disease.
Thus, the new frontiers of experimentation focus on the production of nanoparticles for a more controllable delivery of drugs and the precise targeting of specific patterns to reduce stress and block the mechanism of PTSD
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