Lucas Ferreira Varela Cancado
Design of an integrated control system for temperature focusing in microwave cancer hyperthermia.
Rel. Giuseppe Vecchi. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Elettronica (Electronic Engineering), 2026
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Abstract
Microwave hyperthermia is a medical technique used as an adjuvant therapy in cancer treatment, where tumor tissues are selectively heated to approximately 42–44 °C using non-ionizing microwave radiation. When applied together with chemotherapy and/or radiotherapy, this controlled heating has been shown to significantly improve therapeutic outcomes. The elevated temperature increases tumor cell sensitivity to radiation and enhances the uptake of anticancer drugs, thereby boosting the effectiveness of conventional treatments without introducing additional toxicity. Achieving accurate and uniform heating of the tumor area, while preserving surrounding healthy tissue, is essential for a successful therapy. For this reason, phased antenna arrays are employed to carefully focus the specific absorption rate (SAR) in the tumor region.
This is accomplished through dedicated optimization algorithms supported by numerical simulations and a closed-loop electronic control system, which continuously supplies the antennas with the optimized feeding coefficients throughout the entire heating procedure
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