Nowadays, the increasing demand for resilient and sustainable structures leads to design strategies that go beyond probabilistic criteria based on building’s life-safety. Performance-based seismic design approach assesses building and determines the probability of experiencing a certain loss. The current work examines a steel Moment Resisting Frame office building, located in L’Aquila, Italy, by applying FEMA P-58 framework. Losses assessment is performed, comparing the EC8 design scenario (PACT’s intensity-based analysis) and 2009 L’Aquila earthquake scenario (PACT’s scenario-based analysis). Annualized probabilities are computed as well through PACT’s time-based performance assessment, developing building’s life cycle cost analysis. The Moment Resisting Frame is designed through EC3 and EC8 rules, attending to ductility criteria and capacity design (i.e.