Matilde Maoli
Design of polymer-lipid hybrid nanoparticles for the delivery of messenger RNA to T-lymphocytes.
Rel. Valeria Chiono, Letizia Nicoletti, Clara Mattu, Claudia Voena. Politecnico di Torino, Master of science program in Biomedical Engineering, 2025
Abstract
This thesis focuses on the physicochemical characterization and in vitro validation of polymer-lipid hybrid nanoparticles for the specific delivery of messenger RNA (mRNA) to T-lymphocytes in CAR T therapy. Thesis activity was performed in collaboration with Fondazione Umberto Veronesi.
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