Patient-specific coronary hemodynamics, based on medical imaging and Computational Fluid Dynamics (CFD) simulations, plays a critical role in cardiovascular research, as approximately one-third of cardiovascular-related deaths result from coronary artery stenosis. Growing evidence demonstrates that Wall Shear Stress (WSS) has a significant prognostic value in predicting lesions potentially responsible for myocardial infarction in stenotic coronary arteries. Although CFD simulations are considered the optimal approach to obtain a realistic assessment of WSS, their high computational cost combined with the need for specialized users has motivated the development of clinical software able to perform CFD simulations in times compatible with clinical practice, directly in the cath lab by clinicians.