Atherosclerosis is a chronic and progressive inflammatory disease that mainly affects older individuals in industrialized countries. It affects the walls of medium and large blood vessels, such as the coronary arteries, where the formation of atherosclerotic plaques in the tunica intima causes a reduction in the vascular lumen. This narrowing can lead to several clinical complications, including a reduction in blood supply downstream of the lesion, with a consequent risk of ischemia and myocardial infarction. Numerous studies have shown that specific hemodynamic conditions, particularly the presence of disturbed flow, play a crucial role in the development and progression of atherosclerosis. In this scenario, the present thesis analyzes the correlation between hemodynamics and structural characteristics of atherosclerotic plaques in ten models of pathological coronary arteries, reconstructed from CT images, with the aim of identifying the areas predisposed to unfavourable clinical events or formation of new lesions.