Bone scaffolds have emerged as a key solution in tissue engineering for the repair of bone defects, with the objective of replicating the morphological and mechanical properties of the native bone. Triply Periodic Minimal Surfaces (TPMS) unit cells, characterized by their smooth and continuous geometry, represent an excellent solution for the design of lattice structures for bone scaffolds. In this thesis a computational framework has been implemented to design bone scaffolds based on TPMS unit cells with different geometries and configurations. The framework was developed in Matlab and it is based on the open-source toolboxes “LatticeWorks” and “GIBBON,” integrated with “TetGen” for unit cell generation and tetrahedral mesh creation.