This thesis aims to provide a practical and adaptable guide for companies in Italy planning to organize events within temporary or mobile construction sites (cantieri temporanei o mobili), ensuring full compliance with occupational health and safety (OSH) Italians regulations, particularly those outlined in Legislative Decree 81/2008 and relevant European standards. Using the “ex Macello” site in Milan, currently undergoing demolition and environmental remediation, as a case study, and with technical input from GAe Engineering S.r.l., the firm responsible for OSH management at the site, the thesis outlines a structured five-part framework: site contextualization, preparatory steps by the organizing company, safety measures for temporary installations, operational safety during the event, and post-event dismantling procedures, including final risk assessment.