In vivo, physical forces are essential regulators of stem cell behavior within their native microenvironments and contribute significantly to the structural and functional maturation of developing tissues. Cardiac and skeletal muscles, in particular, are constantly exposed to intense physical stimulation, including continuous electrical impulses that induce contraction. In this context, traditional two-dimensional (2D) static cultures, such as Petri dishes and flasks, fail to replicate the three-dimensional (3D) architecture and dynamic nature of the in vivo environment, often leading to non-predictive outcomes. To address these limitations, dynamic culture devices, namely bioreactors, have emerged as a pivotal investigation tool in cardiac and skeletal muscle tissue engineering.