In the context of extending human presence into deep space, particularly on the Moon, in-situ resource utilization (ISRU) is essential for sustaining long-term missions. This study investigates water purification system designed to treat synthetic water containing methanol, simulating volatile impurities typically found in regolith-derived condensate streams. The system combines direct contact membrane distillation (DCMD), UV photolysis and hydrolysis. Experiments were conducted using methanol concentrations of 30 mg/L and 100 mg/L at varying temperatures. direct contact membrane distillation (DCMD) demonstrated efficient methanol transport, achieving a recovery rate of up to 40.2% at 50°C for 30 mg/L concentration. However, higher temperatures accelerated feed depletion and reduced selectivity because of the increased water vapor flux.