The main objective of this study is the development and dynamic analysis of a scaled prototype model of the Messina Strait Bridge under seismic loading. A physical model was constructed in the laboratory at a scale of 1/265. To simulate the soil-structure interaction (SSI), a spring-box system was designed and implemented, allowing the study of three different soil conditions: soft, medium, and hard soils. Additionally, the dynamic behavior of the bridge under damaged cable conditions was investigated. Finite Element Analysis was used to identify optimal sensor placement points, including Fiber Bragg Grating (FBG), Linear Variable Differential Transformers (LVDT), and accelerometers. However, the experimental verification of the model’s seismic response is still pending, as the software MIDAS Civil does not currently support the application of ground motions to damaged configurations.