The rising environmental awareness is leading scientists to find more sustainable technologies and materials to substitute the ones that have negative impacts on the ecosystems. Particularly, natural and sustainable polymers, such as cellulose, are under investigation to find out whether they can be substitutes for petroleum based polymers in numerous applications (e.g. packaging, cosmetics industry) In this work, the behaviors of nano fibrils and nanocrystalline cellulose materials, derived from plant and food grade, were analyzed in test media mimicking many environmental waters’ conditions. Size and stability of NC particles, which were extracted from primary source using chemical and physical pre-treatment, were determined by Dynamic Light Scattering (DLS) and Nanoparticle Tracking Analysis (NTA).