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Development of functionalized hybrid nanoparticles for selective delivery of microRNA towards skeletal muscle cells

Martina De Carolis

Development of functionalized hybrid nanoparticles for selective delivery of microRNA towards skeletal muscle cells.

Rel. Valeria Chiono, Clara Mattu, Letizia Nicoletti, Camilla Paoletti, Giovanni Paolo Stola. Politecnico di Torino, Master of science program in Biomedical Engineering, 2024

Abstract:

This thesis focuses on the formulation and optimization of functionalized hybrid nanoparticles for active targeting towards skeletal muscle cells in order to provide an effective delivery system for therapeutic miRNAs against genetic disorders affecting skeletal muscles. This work was part of BIORECAR ERC project (contract nr: 772168, www.biorecar.polito.it), POLIRNA ERC PoC project (contract nr: 101113522) and AFM Telethon SaveAR project.
Relators: Valeria Chiono, Clara Mattu, Letizia Nicoletti, Camilla Paoletti, Giovanni Paolo Stola
Academic year: 2024/25
Publication type: Electronic
Number of Pages: 104
Additional Information: Tesi secretata. Fulltext non presente
Subjects:
Corso di laurea: Master of science program in Biomedical Engineering
Classe di laurea: New organization > Master science > LM-21 - BIOMEDICAL ENGINEERING
Aziende collaboratrici: UNSPECIFIED
URI: http://webthesis.biblio.polito.it/id/eprint/33752
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