In the realm of decarbonization and clean technologies, whose future development will affect the evolution of the energy systems known today, green hydrogen is becoming a major contributor. It can be produced through the electrolysis process from water, exploiting green electricity from renewable energy sources to avoid GHG emissions. The aim of this study is to analyze the development of the Crete-Aegean Hydrogen Valley, known as the CRAVE-H2 project, where most aspects of the supply chain of green hydrogen are addressed. Located on the island of Crete, its strategic position allows the exploitation of electric and gas network connections between the European and African continents, as well as the favourable Mediterranean weather supplying high RES electricity production.