Valentina Benna
Design of a musculoskeletal modeling pipeline to uncover the impact of spinal sagittal alignment on intervertebral joint loads.
Rel. Mara Terzini, Simone Borrelli, Giovanni Putame. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Biomedica, 2024
Abstract
Background: Sagittal alignment describes the curvature of the spine in the sagittal plane. Despite the high variability in the normal sagittal alignment, a previous study conducted by Roussouly et al. identified four different types of sagittal profiles (type 1-4) in which human spine can be classified. Since sagittal alignment degeneration can lead to spinal diseases and deformities, causing pain and disability, clinical and numerical research have focused on understanding the relation between sagittal alignment, spinal loading and pathology. Aim: As there is no database of musculoskeletal models associated with different Roussouly types in literature, an algorithm was specifically developed to generate models classifiable according to Roussouly types.
Materials and Methods: Two hundred models were created for each type, starting from a validated female reference model characterized by a fully articulated thoracolumbar segment and Millard formulation for muscular activity (Burkhart K., 2021, Thoracolumbar spine and rib cage model in OpenSim, OpenSim)
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