Silvia Veglioni
Flexible electrochemical microelectrodes integration in clot-in-chip devices for calcium monitoring.
Rel. Matteo Cocuzza. Politecnico di Torino, Master of science program in Electronic Engineering, 2024
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Abstract
Recent advances in the medical research field have expanded into the use of microfluidics devices, offering innovative solutions for healthcare challenges. Precise control over fluid manipulation at small scales and significant sample volume reduction are just some of the different benefits introduced by these advanced microdevices. In the framework of the European project ANGIE (MAgnetically steerable wireless Nanodevices for the tarGeted delivery of therapeutic agents in any vascular rEgion of the body), focus on exploring the potential use of mobile microrobotic platforms for clot removal. The use of microfluidic devices is key to control the generation of blood clots in confined spaces.
By exploiting controlled diffusion conditions in microfluidic technologies, it is possible to obtain biomimetic blood clots in chip that are of great interest as model systems to study stroke-related diseases
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