Peptides therapeutics is an upcoming research field and in the last years many papers have been published with promising results. A deep dive in small contigs (500 Da – 5000Da) could reveal a multitude of potential drugs against several diseases. Synthetized or natural molecules are the two main categories of study for drug development. Especially, the second variety includes a remarkable group of peptides which is the one derived from plants and is characterized by a cysteine motif. Thanks to their anti-fungal activity and their role in the plant immune system, these peptides are rising interest in scientific community. Here in this study, a database of 1000 plant peptides is analysed against known cysteine rich peptide family spacings.