Martina Tierno
Impact of commercial coronary stent cell shape and strut thickness on the hemodynamic-related risk of in-stent restenosis: a computational study.
Rel. Claudio Chiastra, Giuseppe De Nisco. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Biomedica, 2024
Abstract
Coronary atherosclerosis is a globally widespread cardiovascular disease, consisting in a stiffening of the coronary wall with the formation of plaques, narrowing the lumen, and potentially causing insufficient oxygen supply to myocardium or completely occlusion of the coronary artery with subsequent myocardial infarction. The most common treatment for coronary artery revascularization is percutaneous coronary intervention with stent implantation. Stents are expandable tubular mesh structures that are inserted into the atherosclerotic arteries to provide mechanical support to the vessel and restore normal blood flow. Coronary stents are classified based on material, structure and properties, into three main categories: bare metal stents (BMS), drug-eluting stent (DES), and bioresorbable stents (currently under investigation).
However, stent placement may lead to adverse outcomes such as in-stent restenosis (ISR)
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