The aim of this Master Thesis work is to develop targeted nanocarriers for drug delivery acting as a synergistic anticancer therapy in Multiple Myeloma (MM). These drug-loaded nanocarriers, thanks to their surface functionalization, can selectively target cancer cells and be internalized by them, avoiding the high toxicity and other side-effects of conventional antitumor therapies. Two different kinds of nanocarriers have been developed: liposomes and lipid-coated Mesoporous Silica Nanoparticles (MSNs). Liposomes, which are spherical vesicles having at least one lipid bilayer, have been prepared using a thin film hydration method and extrusion, to obtain monodisperse suspensions of unilamellar vesicles (about 100 nm).