Finite element (FE) models derived from microcomputed tomography (μCT) images are often used to non-invasively estimate the mechanical properties of trabecular bone. Traditionally, image 3D voxels are directly converted into hexahedral elements, generating voxel-FE models that are reliable but computationally very demanding. Tetrahedral FE models (tetra-FE) offer greater computational efficiency but are less frequently used, likely due to complexities in mesh parameter definition and risk of element distortion. Ciclope is an open-source package, written in Python, that facilitates the preprocessing of μCT data to generate voxel-FE and tetra-FE. This study aimed to verify the robustness and accuracy of the computationally efficient tetra-FE approach, through a convergence test on the main mesh parameters and a comparison of results with the standard voxel-FE approach.