In cases where muscle injuries result in damage surpassing the natural regenerative capacity of skeletal muscle tissue, a surgical approach is necessary, typically involving prosthetic implantation or the grafting of material from a donor. This approach often brings complications such as donor site morbidity, a shortage of material for autografts, or the lifelong requirement for immunosuppressant therapy to prevent rejection in the case of allografts. To tackle this issue, recent research has concentrated on the in-vitro engineering of grafts that employ patient-derived skeletal muscle cells to populate a three-dimensional structure capable of mimicking physiological tissue. These constructs could also serve to develop in-vitro skeletal muscle tissue models.