Giulia Bolmida
An idealized computational fluid dynamics study comparing the hemodynamic performance of closed- and open-cell coronary stent designs.
Rel. Claudio Chiastra, Giuseppe De Nisco. Politecnico di Torino, Master of science program in Biomedical Engineering, 2023
Abstract
Coronary atherosclerosis is a widely prevalent and life-threatening cardiovascular disease caused by the accumulation of lipids in the coronary artery walls. This disease results in a progressive reduction of the luminal cross-sectional area available to the passage of blood flow, thus increasing the risk of myocardial infarction. There are several approaches to treat the disease and its consequences. Today percutaneous coronary intervention (PCI), which consists in the implantation of a stent within the artery, is the most common one. Coronary stents have revolutionized the treatment of coronary artery disease by providing a less invasive approach than open-heart surgery. Stents are expandable tube-shaped structures, generally thin and mesh-like.
After their expansion, they provide mechanical support to the vessel wall, by restoring its physiological condition
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