Currently, understanding the pressure within an arterial pathway plays a crucial role in various applications. These areas range from the placement of devices like stents within arteries to the detailed analysis of perfusion in specific regions, such as those near a tumor. Therefore, the ability to obtain precise measurements of pressure within arterial segments is of paramount importance. During this thesis, I focused on the analysis of an endovascular pressure sensor based on fiber optics. The approach was divided into three main phases: the first involves hemodynamic simulations aimed at understanding pressure variations within vessels with specific characteristics; the second phase focused on creating a polymer coating on the sensitive part of the optical fiber, with the aim of improving its sensitivity; finally, the third part concerns the development of two models (Phantoms) of brain portions (occipital area) with and without a tumour mass surrounding the blood vessel, in order to study the impact on blood pressure.