In this document, the DELPHI approach is deployed to investigate the impact of blockchain technology, ICOs, and cryptocurrency regulation in Colombia and developing countries. These new technologies have already developed dynamics in recent years, which will be analyzed and discussed through this document to define the role of the State and its companies and investors in the medium and long term concerning adopting these technologies as impact tools. Similar research by authors in the Colombian context is analyzed, as well as the main applied comparative advantages of blockchain technologies and tokenization focused on companies. These technologies' globalized capacity and peer-to-peer advantages in terms of security, traceability, and speed are essential for an economy that wants to increase its reach and productive capacity.