This thesis work, conducted at SynArea Consultants S.R.L., examines the potential applications of the Metaverse in the field of rehabilitation, with a specific focus on individuals affected by neurodegenerative syndromes and their physical and cognitive stimulation. The Meta Quest 2 VR headset is chosen for accessing the virtual world due to its favorable technical features and cost-effectiveness, especially considering its potential extension to a home-based setting. Furthermore, the recent software updates to the hand-tracking features of this device align well with our objectives removing the need for controllers. A home-like environment is selected to mitigate potential anxiety in users unfamiliar with the surroundings.