This thesis focuses on the analysis and design of a communication subsystem for the HENON satellite, a 12U CubeSat that will be used for a space weather monitoring mission in a distant retrograde orbit (DRO) in the Earth-Sun system. The study explores the state-of-the-art CubeSat technology for deep space communication, including communication standards and protocols specific to space applications. The conducted activities include the definition of the Telemetry, Tracking, and Command (TT&C) subsystem requirements, the design of the communication subsystem, the definition and trade-off analysis of radio frequency interfaces, the assessment of radiometric and navigation techniques, as well as the antenna system design.